Degradable Polyelectrolyte Multilayers that Promote the Release of siRNA
نویسندگان
چکیده
منابع مشابه
Degradable polyelectrolyte multilayers that promote the release of siRNA.
We report an approach to the design of degradable polyelectrolyte-based films for the controlled release of siRNA from surfaces. Our approach is based on stepwise, layer-by-layer assembly of multilayered polyelectrolyte films (or "polyelectrolyte multilayers", PEMs) using siRNA and a hydrolytically degradable poly(β-amino ester) (polymer 1). Fabrication of films using siRNA sequences for green ...
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The elastic properties of nanotubes fabricated by layer-by-layer (LbL) assembly of polyelectrolytes in the nanopores of polycarbonate track-etched membranes have been investigated by resonant contact Atomic Force Microscopy (AFM), for nanotube diameters in the range of 100 to 200 nm. The elastic modulus of the nanotubes was computed from the resonance frequencies of a cantilever resting on free...
متن کاملPatterned Microstructure Fabrication: Polyelectrolyte Complexes vs Polyelectrolyte Multilayers
Polyelectrolyte complexes (PEC) are formed by mixing the solutions of oppositely charged polyelectrolytes, which were hitherto deemed "impossible" to process, since they are infusible and brittle when dry. Here, we describe the process of fabricating free-standing micro-patterned PEC films containing array of hollow or filled microchambers by one-step casting with small applied pressure and a P...
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ژورنال
عنوان ژورنال: Langmuir
سال: 2011
ISSN: 0743-7463,1520-5827
DOI: 10.1021/la200815t